Apoptosis,Cancer,Cell Cycle,Cell Death,Epigenetics and Nuclear Signaling,Metabolism,Metabolism Processes,Nuclear,Pathways and Processes,Protein Phosphorylation,Ser/Thr Kinases,Serine/Threonine Kinases,Signal Transduction
Aditional Names:
RAC-alpha serine/threonine-protein kinase;2.7.11.1;Protein kinase B;PKB;Protein kinase B alpha;PKB alpha;RAC-PK-alpha;Akt1;
Unit:
10ug 100 ?g/vial
Concentration:
Adding 1 ml of PBS buffer will yield a concentration of 100 ?g/ml.
Clonality:
Monoclonal
Price:
Consultar
Format:
Lyophilized
Immunogen:
Synthetic peptide corresponding to amino acids 461-4
Host:
Mouse
Reactivity:
Chicken, Human, Mouse, Rat
Cross Reactivity:
No cross-reactivity with other proteins
Application:
WB
Description:
Boster Bio Anti-PKB Alpha Akt1 Antibody (Monoclonal, PKB-175) catalog # MA1085. Tested in WB applications. This antibody reacts with Chicken, Human, Mouse, Rat.
Function:
AKT1 is one of 3 closely related serine/threonine- protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine
Cell localization:
Cytoplasm. Nucleus. Cell membrane. Nucleus after activation by integrin-linked protein kinase 1 (ILK1). Nuclear translocation is enhanced by interaction with TCL1A (By similarity). Phosphorylation on Tyr-176 by TNK2 results in its localization to the cel
Clone:
Clone: PKB-175
Isotype:
Mouse IgG1
Purification:
Ascites
Storage conditions:
Store at -20?C for one year from date of receipt. After reconstitution, at 4?C for one month. It can also be aliquotted and stored frozen at -20?C for six months. Avoid repeated freeze-thaw cycles.
Assay inforation:
Western blot, 0.25-0.5?g/ml, Human, mouse, rat, chicken
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