Neurogenic locus notch homolog protein 1; Notch 1; hN1; Translocation-associated notch protein TAN-1; Notch 1 extracellular truncation; NEXT; Notch 1 intracellular domain; NICD; NOTCH1; TAN1;
Unit:
96 wells/kit, with removable strips.
Price:
Consultar
Immunogen:
Expression system for standard: NS0; Immunogen seque
Reactivity:
Human
Cross Reactivity:
There is no detectable cross-reactivity with other relevant proteins.
Application:
ELISA
Description:
Human NOTCH1 / TAN 1 ELISA Kit PicoKine® (96 Tests). Quantitate Human NOTCH1 in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 12pg/ml.
Function:
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSU
Cell localization:
Cell membrane; Single-pass type I membrane protein.
Storage conditions:
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
Assay inforation:
Dilution ratio of 1:1, concentration in serum and plasma is around 1600 pg/ml.
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