Supplier: | Boster |
---|---|
Reference: | M00116 |
Name: | Anti-YAP1/Yap Rabbit Monoclonal Antibody |
Category: | Antibody |
Subcategory: | Primary Antibodies,Rabbit Monoclonal Antibodies |
Research Area: | Adapters,Cancer,Cancer Susceptibility,Cytoplasmic,Epigenetics and Nuclear Signaling,Protein Phosphorylation,Proto-Oncogenes,Signal Transduction,Transcription,Transcription Factors,Tyrosine Kinases |
Aditional Names: | Transcriptional coactivator YAP1;Yes-associated protein 1;Protein yorkie homolog;Yes-associated protein YAP65 homolog;YAP1;YAP65; |
Unit: | 30ul 100 ?l |
Concentration: | Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
Clonality: | Monoclonal |
Price: | Consultar |
Format: | Liquid |
Immunogen: | A synthesized peptide derived from human YAP1 |
Host: | Rabbit |
Reactivity: | Human |
Application: | Flow Cytometry,IP,IF,IHC,ICC,WB |
Description: | Boster Bio Anti-YAP1/Yap Rabbit Monoclonal Antibody catalog # M00116. Tested in Flow Cytometry, IP, IF, IHC, ICC, WB applications. This antibody reacts with Human. |
Function: | Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting prolifera |
Cell localization: | Cytoplasm. Nucleus. Both phosphorylation and cell density can regulate its subcellular localization. Phosphorylation sequesters it in the cytoplasm by inhibiting its translocation into the nucleus. At low density, predominantly nuclear and is translocate |
Clone: | Clone: CIE-25 |
Isotype: | Rabbit IgG |
Purification: | Affinity-chromatography |
Storage conditions: | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Assay inforation: | WB 1:5000-1:10000 IHC 1:50-1:100 ICC/IF 1:50-1:100 IP 1:50 Flow Cytometry 1:50 |