Synthesized peptide derived from Internal of human G
Host:
Rabbit
Reactivity:
Human, Mouse
Application:
WB,IHC
Description:
Boster Bio Anti-Cyclin-G-associated kinase GAK Antibody (Catalog # A04246). Tested in WB, IHC applications. This antibody reacts with Human, Mouse.
Function:
Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin- coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.
Cell localization:
Cytoplasm, perinuclear region. Golgi apparatus, trans-Golgi network. Cell junction, focal adhesion. Localizes to the perinuclear area and to the trans-Golgi network. Also seen on the plasma membrane, probably at focal adhesions.
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage conditions:
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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