Anti-Cyclin-G-associated kinase GAK Antibody

Supplier: Boster
Reference: A04246
Name: Anti-Cyclin-G-associated kinase GAK Antibody
Category: Antibody
Subcategory: Primary Antibodies
Research Area: Cell Biology,Cell Cycle,Kinases/Phosphatases,Protein Phosphorylation,Ser/Thr Kinases,Signal Transduction
Aditional Names: Cyclin-G-associated kinase;2.7.11.1;GAK;
Unit: 100ul
Concentration: 1 mg/ml
Clonality: Polyclonal
Price: Consultar
Format: Liquid
Immunogen: Synthesized peptide derived from Internal of human G
Host: Rabbit
Reactivity: Human, Mouse
Application: WB,IHC
Description: Boster Bio Anti-Cyclin-G-associated kinase GAK Antibody (Catalog # A04246). Tested in WB, IHC applications. This antibody reacts with Human, Mouse.
Function: Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin- coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.
Cell localization: Cytoplasm, perinuclear region. Golgi apparatus, trans-Golgi network. Cell junction, focal adhesion. Localizes to the perinuclear area and to the trans-Golgi network. Also seen on the plasma membrane, probably at focal adhesions.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Assay inforation: Western blotting: 1:500~1:3000