| Supplier: | Boster |
|---|---|
| Reference: | A30437 |
| Name: | Anti-Chk1 CHEK1 Antibody |
| Category: | Antibody |
| Subcategory: | Primary Antibodies |
| Research Area: | Kinases/Phosphatases |
| Aditional Names: | CHEK1;CHK1;Serine/threonine-protein kinase Chk1;CHK1 checkpoint homolog;Cell cycle checkpoint kinase;Checkpoint kinase-1 |
| Unit: | 100ul |
| Concentration: | 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
| Clonality: | Polyclonal |
| Price: | Consultar |
| Format: | Liquid |
| Immunogen: | A peptide derived from human Chk1. Immunogen sequenc |
| Host: | Rabbit |
| Reactivity: | Human, Mouse, Rat |
| Application: | WB,IF,ICC,ELISA |
| Description: | Boster Bio Anti-Chk1 CHEK1 Antibody (Catalog# A30437). Tested in WB, IF, ICC, ELISA applications. This antibody reacts with Human, Mouse, Rat. |
| Function: | Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. May also negatively regulate cell cycle progression during unperturbed |
| Cell localization: | Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nuclear export is mediated at least in part by XPO1/CRM1. Also localizes to the centrosome specifically during interphase, where it may protect centrosomal CDC2 kinase |
| Isotype: | Rabbit IgG |
| Purification: | The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen. |
| Storage conditions: | Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Assay inforation: | Western Blot, 1:500 - 1:2000 Immunofluorescence, 1:200 - 1:1000 ELISA, 1:10000 Not yet tested in other applications. |