Mitogen-activated protein kinase kinase kinase 8;2.7.11.25;Cancer Osaka thyroid oncogene;Proto-oncogene c-Cot;Serine/threonine-protein kinase cot;Tumor progression locus 2;TPL-2;MAP3K8;COT, ESTF;
Unit:
100ul
Price:
Consultar
Format:
Liquid
Immunogen:
Synthesized peptide derived from human Cot around th
Host:
Rabbit
Reactivity:
Human, Mouse, Rat
Application:
WB
Description:
Boster Bio Anti-COT MAP3K8 Antibody catalog # A01696. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Function:
Required for lipopolysaccharide (LPS)-induced, TLR4- mediated activation of the MAPK/ERK pathway in macrophages, thus being critical for production of the proinflammatory cytokine TNF- alpha (TNF) during immune responses. Involved in the regulation of T-
Cell localization:
Cytoplasm.
Isotype:
IgG
Purification:
Immunogen affinity purified
Storage conditions:
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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