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Anti-BARD1 Antibody

Supplier: Boster
Reference: A01646
Name: Anti-BARD1 Antibody
Category: Antibody
Subcategory: Primary Antibodies
Research Area: Apoptosis,Cancer,Cancer Susceptibility,Cell Biology,Cell Cycle,Cell Death,DNA/RNA,DNA Damage & Repair,DNA Damage Response,Epigenetics and Nuclear Signaling,Metabolism,Metabolism Processes,Nuclear,Oncoproteins/Suppressors,Pathways and Processes,Proteasome
Aditional Names: BRCA1-associated RING domain protein 1;BARD-1;6.3.2.-;BARD1;
Unit: 100ul
Concentration: 1 mg/ml
Clonality: Polyclonal
Price: Consultar
Format: Liquid
Immunogen: Synthesized peptide derived from N-terminal of human
Host: Rabbit
Reactivity: Human
Application: WB
Description: Boster Bio Anti-BARD1 Antibody (Catalog # A01646). Tested in WB applications. This antibody reacts with Human.
Function: Probable E3 ubiquitin-protein ligase. The BRCA1-BARD1 heterodimer specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptiona
Cell localization: Nucleus. During S phase of the cell cycle, colocalizes with BRCA1 into discrete subnuclear foci. Can translocate to the cytoplasm. Localizes at sites of DNA damage at double-strand breaks (DSBs); recruitment to DNA damage sites is mediated by the BRCA1-A
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Assay inforation: Western blotting: 1:500~1:3000
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