| Supplier: | Boster |
|---|---|
| Reference: | A05659-1 |
| Name: | Anti-ERN2 Antibody |
| Category: | Antibody |
| Subcategory: | Primary Antibodies |
| Research Area: | Apoptosis,Cell Biology,DNA/RNA,Epigenetics and Nuclear Signaling,Intracellular,Kinases,Protein Phosphorylation,Ser/Thr Kinases,Signal Transduction,Translation |
| Aditional Names: | ERN2;IRE2;Serine/threonine-protein kinase/endoribonuclease IRE2;Endoplasmic reticulum-to-nucleus signaling 2;Inositol-requiring protein 2;hIRE2p;Ire1-beta;IRE1b |
| Unit: | 100ul |
| Concentration: | 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
| Clonality: | Polyclonal |
| Price: | Consultar |
| Format: | Liquid |
| Immunogen: | A peptide derived from human ERN2. Immunogen sequenc |
| Host: | Rabbit |
| Reactivity: | Human, Mouse |
| Application: | IHC-P,IF,ICC,ELISA |
| Description: | Boster Bio Anti-ERN2 Antibody (Catalog# A05659-1). Tested in IHC-P, IF, ICC, ELISA applications. This antibody reacts with Human, Mouse. |
| Function: | Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins. |
| Cell localization: | Endoplasmic reticulum membrane; Single-pass type I membrane protein. |
| Isotype: | Rabbit IgG |
| Purification: | The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen. |
| Storage conditions: | Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Assay inforation: | Immunohistochemistry, 1:100 - 1:300 Immunofluorescence, 1:200 - 1:1000 ELISA, 1:10000 Not yet tested in other applications. |