Supplier: | Boster |
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Reference: | P30917 |
Name: | Anti-Phospho Tensin-2 (Tyr483) Antibody |
Category: | Antibody |
Subcategory: | Primary Antibodies |
Research Area: | Protein Phosphorylation,Ser/Thr Kinases,Signal Transduction |
Aditional Names: | TENC1;KIAA1075;TNS2;Tensin-like C1 domain-containing phosphatase;C1 domain-containing phosphatase and tensin homolog;C1-TEN;Tensin-2 |
Unit: | 100ul |
Concentration: | 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
Clonality: | Polyclonal |
Price: | Consultar |
Format: | Liquid |
Immunogen: | A phospho-peptide derived from human Tensin-2 around |
Host: | Rabbit |
Reactivity: | Human, Mouse |
Application: | WB,ELISA |
Description: | Boster Bio Anti-Phospho Tensin-2 (Tyr483) Antibody (Catalog# P30917). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse. |
Function: | Regulates cell motility and proliferation. May have phosphatase activity. Reduces AKT1 phosphorylation. Lowers AKT1 kinase activity and interferes with AKT1 signaling. |
Cell localization: | Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Detected at the end of actin stress fibers. Detected in cytoplasmic punctate bodies (PubMed:22019427). |
Isotype: | Rabbit IgG |
Purification: | The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide. |
Storage conditions: | Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Assay inforation: | Western Blot, 1:500 - 1:2000 ELISA, 1:10000 Not yet tested in other applications. |