Supplier: | Boster |
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Reference: | M00004 |
Name: | Anti-Catenin, beta (p120) CTNNB1 Monoclonal Antibody |
Category: | Antibody |
Subcategory: | Primary Antibodies,Monoclonal Antibodies |
Research Area: | Actin, etc.,Atherosclerosis,Cadherins,Cancer,Cardiovascular,Cell Adhesion,Cytoplasmic,Cytoskeleton,Cytoskeleton/ECM,Invasion/Microenvironment,Microfilaments,Neurogenesis,Neurology Process,Neuroscience,Signal Transduction,Signaling Pathways,Stem Cells,Vasc |
Aditional Names: | Catenin beta-1;Beta-catenin;CTNNB1;CTNNB;OK/SW-cl.35, PRO2286; |
Unit: | 100ug |
Concentration: | Purified antibody with BSA and azide at 200ug/ml |
Clonality: | Monoclonal |
Price: | Consultar |
Format: | Liquid |
Immunogen: | Recombinant chicken ?-catenin |
Host: | Mouse |
Reactivity: | Human, Mouse, Rat, Goat, Dog, Chicken |
Application: | Flow Cytometry,IF,WB,IHC |
Description: | Boster Bio Anti-Catenin, beta (p120) CTNNB1 Monoclonal Antibody (Catalog # M00004). Tested in Flow Cytometry, IF, WB, IHC applications. This antibody reacts with Human, Mouse, Rat, Cow, Dog, Chicken. |
Function: | Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and i |
Cell localization: | Cell Surface and Cytoplasmic |
Clone: | Clone: 15B8 |
Isotype: | IgG1, kappa |
Purification: | 200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G. |
Storage conditions: | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
Assay inforation: | Flow Cytometry (1-2ug/million cells) Immunofluorescence (1-2ug/ml) Western Blot (1-2ug/ml) Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with |