| Supplier: | Boster |
|---|---|
| Reference: | M00005 |
| Name: | Anti-BRCA1 (Breast Marker) Monoclonal Antibody |
| Category: | Antibody |
| Subcategory: | Primary Antibodies,Monoclonal Antibodies |
| Research Area: | Cancer,Cancer Susceptibility,Cell Biology,Chromatin Modifying Enzymes,DNA/RNA,DNA Damage & Repair,DNA Damage Response,Epigenetics and Nuclear Signaling,Oncoproteins/Suppressors,Proteasome / Ubiquitin,Proteolysis/Ubiquitin,Ring Finger E3 Ligase,Transcripti |
| Aditional Names: | Breast cancer type 1 susceptibility protein;6.3.2.-;RING finger protein 53;BRCA1;RNF53; |
| Unit: | 100ug |
| Concentration: | Purified antibody with BSA and azide at 200ug/ml |
| Clonality: | Monoclonal |
| Price: | Consultar |
| Format: | Liquid |
| Immunogen: | Recombinant human BRCA1 protein fragment (around aa4 |
| Host: | Mouse |
| Reactivity: | Human |
| Application: | IHC |
| Description: | Boster Bio Anti-BRCA1 (Breast Marker) Monoclonal Antibody (Catalog # M00005). Tested in IHC applications. This antibody reacts with Human. |
| Function: | E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of o |
| Cell localization: | Cytoplasmic and Nuclear |
| Clone: | Clone: BRCA1/1398 |
| Isotype: | IgG1, kappa |
| Purification: | 200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G. |
| Storage conditions: | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
| Assay inforation: | Immunohistochemistry (Formalin-fixed) (2-5ug/ml for 60 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes) Optimal diluti |