APOE3 Human Recombinant (19-317) produced in E. coli is a single, non-glycosylated, polypeptide chain containing 306 amino acids and having a molecular mass of 35.2kDa.
The APOE is fused to a Met and a 6 amino acid His tag [M-HHHHHH] at N-terminus and pur
Function:
Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.
Cell localization:
Secreted.
Purification:
Greater than 95% as determined by SDS-PAGE.
Storage conditions:
Store at 4°C if entire vial will be used within 2-4 weeks. Store frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
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