| Supplier: | Boster |
|---|---|
| Reference: | M01972 |
| Name: | Anti-MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1) Monoclonal Antibody |
| Category: | Antibody |
| Subcategory: | Primary Antibodies,Monoclonal Antibodies |
| Research Area: | MAPK Pathway,Protein Phosphorylation,Ser/Thr Kinases,Signal Transduction |
| Aditional Names: | Mitogen-activated protein kinase kinase kinase 1;2.7.11.25;MAPK/ERK kinase kinase 1;MEK kinase 1;MEKK 1;MAP3K1;MAPKKK1, MEKK, MEKK1; |
| Unit: | 100ug |
| Concentration: | Purified antibody with BSA and azide at 200ug/ml |
| Clonality: | Monoclonal |
| Price: | Consultar |
| Format: | Liquid |
| Immunogen: | Partial recombinant MAP3K1 (aa1077-1176) (SKNSMTLDLN |
| Host: | Mouse |
| Reactivity: | Human |
| Application: | WB,IHC |
| Description: | Boster Bio Anti-MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1) Monoclonal Antibody (Catalog # M01972). Tested in WB, IHC applications. This antibody reacts with Human. |
| Function: | Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway. |
| Cell localization: | Cytoplasmic |
| Clone: | Clone: 2F6 |
| Isotype: | IgG2a, kappa |
| Purification: | 200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G. |
| Storage conditions: | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
| Assay inforation: | Western Blot (1-2ug/ml) Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris Buffer with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT |