1 kit, containing two 96-well plates and all necessary reagents
Price:
Consultar
Reactivity:
Human, Mouse, Rat
Application:
ELISA
Description:
The C-RAF (Phospho-Ser642) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor C-RAF (Phospho-Ser642) protein expression profile in cells. The kit can be used for measuring the relative amounts of C-
Function:
Serine/threonine-protein kinase that acts as a regulatory link between the membrane-associated Ras GTPases and the MAPK/ERK cascade, and this critical regulatory link functions as a switch determining cell fate decisions including proliferation, differen
Cell localization:
Cytoplasm. Cell membrane. Mitochondrion. Nucleus. Colocalizes with RGS14 and BRAF in both the cytoplasm and membranes. Phosphorylation at Ser-259 impairs its membrane accumulation. Recruited to the cell membrane by the active Ras protein. Phosphorylation
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