B-cell linker protein;B-cell adapter containing a SH2 domain protein;B-cell adapter containing a Src homology 2 domain protein;Cytoplasmic adapter protein;Src homology 2 domain-containing leukocyte protein of 65 kDa;SLP-65;BLNK;BASH, SLP65;
Unit:
1 kit, containing two 96-well plates and all necessary reagents
Price:
Consultar
Reactivity:
Human, Mouse, Rat
Application:
ELISA
Description:
The BLNK (Phospho-Tyr84) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor BLNK (Phospho-Tyr84) protein expression profile in cells. The kit can be used for measuring the relative amounts of BLNK (
Function:
Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB
Cell localization:
Cytoplasm. Cell membrane. BCR activation results in the translocation to membrane fraction.
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