Component of the post-replicative DNA mismatch repair system (MMR). Forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. When bound, heterod
Cell localization:
Nucleus, Chromosome.
Isotype:
IgG2b
Positive control:
HeLa cell lysate, HEK-293 cell lysate, A549 cell lysate, mouse testis tissue lysate, rat testis tissue lysate, Wild-type SCC7 whole cell lysates, human breast carcinoma tissue, human placenta tissue, rat brain tissue, human kidney tissue.
Storage conditions:
Store at +4? after thawing. Aliquot store at -20?. Avoid repeated freeze / thaw cycles.
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