In mammals, four different isoenzymes exist for pyruvate kinase. Pyruvate kinases are responsible for catalyzing the final step in glycolysis: the conversion of phosphoenolpyruvate to pyruvate with the coinciding generation of ATP. The PKM (pyruvate kinas
Cell localization:
Cytoplasm. Nucleus.
Isotype:
IgG
Positive control:
Wild-type MDA-MB-231 whole cell lysate, SiHa cell lysate, A549 cell lysate, PC-3 cell lysate, A549, F9, PC-3M, human tonsil tissue, human thyroid carcinoma tissue, human colon cancer tissue, human breast cancer tissue.
Storage conditions:
Store at +4? after thawing. Aliquot store at -20?. Avoid repeated freeze / thaw cycles.
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