Recombinant protein within Human ATF6 aa 168-392 / 6
Host:
Rabbit
Reactivity:
Human, Rat
Application:
WB,IF-Cell,IHC-P,FC
Description:
Transmembrane glycoprotein of the endoplasmic reticulum that functions as a transcription activator and initiates the unfolded protein response (UPR) during endoplasmic reticulum stress. Cleaved upon ER stress, the N-terminal processed cyclic AMP-dependen
Cell localization:
Endoplasmic reticulum membrane. Nucleus. Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus. THBS4 promotes its nuclear shuttling.
Isotype:
IgG
Positive control:
Hela, A431, HUVEC, K562, rat brain tissue, human kidney tissue.
Storage conditions:
Store at +4? after thawing. Aliquot store at -20?. Avoid repeated freeze/thaw cycles.
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