Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'L
Cell localization:
Nucleus.
Isotype:
IgG
Positive control:
293T cell lysate, 293 cell lysate, Hela, MCF-7, HepG2, human tonsils tissue, human breast carcinoma tissue.
Storage conditions:
Store at +4? after thawing. Aliquot store at -20? or -80?. Avoid repeated freeze / thaw cycles.
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