Synthetic peptide corresponding to residues surround
Host:
Rabbit
Reactivity:
Human, Mouse
Application:
WB,IF-Cell
Description:
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replic
Cell localization:
Nucleus. Chromosome.
Isotype:
IgG
Positive control:
HeLa treated with 500 ng/mL TSA for 4 hours, HeLa treated with 500 ng/mL TSA for 4 hours cell lysate, NIH/3T3 treated with 500 ng/mL TSA for 4 hours cell lysate.
Storage conditions:
Store at +4? after thawing. Aliquot store at -20?. Avoid repeated freeze / thaw cycles.
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