EC 2.3.2.27, RING finger protein 53, RING-type E3 ubiquitin transferase BRCA1
Unit:
100µg
Clonality:
Monoclonal a
Price:
Consultar
Format:
Purified
Immunogen:
GST fusion protein expressed in E. coli correspondin
Host:
Mouse
Reactivity:
Human
Cross Reactivity:
This antibody recognizes full-length BRCA1, a 220 kD nuclear phosphoprotein, and does not recognize the deltaexon 11 splice variant. In a high proportion of breast and ovarian cancer cell lines, BRCA1 aberrantly mislocates to the cytoplasm. Its usefulness
Application:
WB,IHC-P,IP,IHC
Recomendation of applications:
Immunoblotting: use at 1-10 ug/mL.
Immunoprecipitation: use at 1-10 ug/mL.
Immunohistochemistry: use at 1-10 ug/mL.
Positive controls: Any normal human tissue, especially those containing rapidly proliferating cells, such as lymphoid germinal centers.
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