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Mouse FASL ELISA Kit PicoKine®

Supplier: Boster
Reference: EK0338
Name: Mouse FASL ELISA Kit PicoKine®
Category: ELISA kit
Subcategory: PicoKine® ELISA Kits
Research Area: Hematopoietic Progenitors,Immunology,Innate Immunity,Intracellular,Lymphoid,Receptors,Stem Cells,T Lymphocytic Lineage,TNF Superfamily
Aditional Names: Tumor necrosis factor ligand superfamily member 6;CD95 ligand;CD95-L;Fas antigen ligand;Fas ligand;FasL;CD178;Tumor necrosis factor ligand superfamily member 6, membrane form;Tumor necrosis factor ligand superfamily member 6, soluble form;Receptor-binding FasL ectodomain;Soluble Fas ligand;sFasL;ADAM10-processed FasL form;APL;FasL intracellular domain;FasL ICD;SPPL2A-processed FasL form;SPA;Faslg;Apt1lg1, Cd95l, Fasl, gld, Tnfsf6;
Unit: 96 wells/kit, with removable strips.
Price: Consultar
Immunogen: Expression system for standard: NS0; Immunogen seque
Reactivity: Mouse
Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.
Application: ELISA
Description: Mouse FASL ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Faslg in cell culture supernatants, serum and plasma (heparin, EDTA, citrate). Sensitivity: 10pg/ml.
Function: Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells (PubMed:7511063). Involved in cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development (PubMed:19794494, PubMed:75
Cell localization: Isoform FasL: Cell membrane; Single- pass type II membrane protein. Cytoplasmic vesicle lumen. Lysosome lumen. Is internalized into multivesicular bodies of secretory lysosomes after phosphorylation by FGR and monoubiquitination. Colocalizes with the SPP
Storage conditions: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
Assay inforation: Dilution ratio of 1:1, concentration in serum and plasma is 0-165 pg/ml.
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