| Supplier: | Boster |
|---|---|
| Reference: | M00159 |
| Name: | Anti-CDK4 Rabbit Monoclonal Antibody |
| Category: | Antibody |
| Subcategory: | Primary Antibodies,Rabbit Monoclonal Antibodies |
| Research Area: | Cancer,Cell Biology,Cell Cycle,Epigenetics and Nuclear Signaling,Kinases/Phosphatases |
| Aditional Names: | Cyclin-dependent kinase 4;2.7.11.22;Cell division protein kinase 4;PSK-J3;CDK4; |
| Unit: | 30ul 100 ?l |
| Concentration: | Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
| Clonality: | Monoclonal |
| Price: | Consultar |
| Format: | Liquid |
| Immunogen: | A synthesized peptide derived from human CDK4 |
| Host: | Rabbit |
| Reactivity: | Human, Mouse, Rat |
| Application: | IP,IF,ICC,WB |
| Description: | Boster Bio Anti-CDK4 Rabbit Monoclonal Antibody catalog # M00159. Tested in IP, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. |
| Function: | Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G (1)/S transition. Phosphorylation of RB1 allows dissociation of t |
| Cell localization: | Cytoplasm. Nucleus. Membrane. Cytoplasmic when non-complexed. Forms a cyclin D-CDK4 complex in the cytoplasm as cells progress through G (1) phase. The complex accumulates on the nuclear membrane and enters the nucleus on transition from G (1) to S phase |
| Clone: | Clone: HOB-3 |
| Isotype: | Rabbit IgG |
| Purification: | Affinity-chromatography |
| Storage conditions: | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Assay inforation: | WB 1:1000-1:2000 ICC/IF 1:50-1:200 IP 1:50 |