Anti-53BP1 TP53BP1 Rabbit Monoclonal Antibody

Supplier: Boster
Reference: M00397
Name: Anti-53BP1 TP53BP1 Rabbit Monoclonal Antibody
Category: Antibody
Subcategory: Primary Antibodies,Rabbit Monoclonal Antibodies
Research Area: Cancer,DNA/RNA,DNA Damage & Repair,DNA Damage Response,Epigenetics and Nuclear Signaling,Oncoproteins/Suppressors,p53 Pathway,Tumor Suppressors
Aditional Names: Tumor suppressor p53-binding protein 1;53BP1;p53-binding protein 1;p53BP1;TP53BP1;
Unit: 30ul 100 ?l
Concentration: Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Clonality: Monoclonal
Price: Consultar
Format: Liquid
Immunogen: A synthesized peptide derived from human 53BP1
Host: Rabbit
Reactivity: Human, Mouse, Rat
Application: Flow Cytometry,IF,IHC,ICC,WB
Description: Boster Bio Anti-53BP1 TP53BP1 Rabbit Monoclonal Antibody catalog # M00397. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
Function: Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53- mediated transcriptional activation.
Cell localization: Nucleus. Chromosome, centromere, kinetochore. Associated with kinetochores. Both nuclear and cytoplasmic in some cells. Recruited to sites of DNA damage, such as double stand breaks. H4K20me2 is required for efficient localization to double strand breaks
Clone: Clone: ABAI-20
Isotype: Rabbit IgG
Purification: Affinity-chromatography
Storage conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Assay inforation: WB 1:500-1:2000
IHC 1:50-1:200
ICC/IF 1:50-1:200
Flow Cytometry 1:50