| Supplier: | Boster |
|---|---|
| Reference: | M02445 |
| Name: | Anti-PABPN1 Rabbit Monoclonal Antibody |
| Category: | Antibody |
| Subcategory: | Primary Antibodies,Rabbit Monoclonal Antibodies |
| Research Area: | Chromatin Binding Proteins,DNA/RNA,DNA/RNA Binding,Epigenetics and Nuclear Signaling,RNA Processing,Splicing,Transcription |
| Aditional Names: | Polyadenylate-binding protein 2;PABP-2;Poly (A)-binding protein 2;Nuclear poly (A)-binding protein 1;Poly (A)-binding protein II;PABII;Polyadenylate-binding nuclear protein 1;PABPN1;PAB2, PABP2; |
| Unit: | 30ul 100 ?l |
| Concentration: | Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
| Clonality: | Monoclonal |
| Price: | Consultar |
| Format: | Liquid |
| Immunogen: | A synthesized peptide derived from human PABPN1 |
| Host: | Rabbit |
| Reactivity: | Human, Mouse |
| Application: | Flow Cytometry,IP,IF,IHC,ICC,WB |
| Description: | Boster Bio Anti-PABPN1 Rabbit Monoclonal Antibody catalog # M02445. Tested in Flow Cytometry, IP, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse. |
| Function: | Involved in the 3'-end formation of mRNA precursors (pre-mRNA) by the addition of a poly (A) tail of 200-250 nt to the upstream cleavage product. Stimulates poly (A) polymerase (PAPOLA) conferring processivity on the poly (A) tail elongation reaction and |
| Cell localization: | Nucleus. Cytoplasm. Nucleus speckle. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Shuttles between the nucleus and the cytoplasm but predominantly found in the nucleus (PubMed:10688363). Its nuclear import may involve the nucleoc |
| Clone: | Clone: AAHI-16 |
| Isotype: | Rabbit IgG |
| Purification: | Affinity-chromatography |
| Storage conditions: | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Assay inforation: | WB 1:500-1:2000 IHC 1:50-1:200 ICC/IF 1:50-1:200 IP 1:50 Flow Cytometry 1:50 |