| Supplier: | Boster |
|---|---|
| Reference: | M00322 |
| Name: | Anti-BACE1/Bace Rabbit Monoclonal Antibody |
| Category: | Antibody |
| Subcategory: | Primary Antibodies,Rabbit Monoclonal Antibodies |
| Research Area: | Alzheimer's Disease,Cell Biology,Neurodegenerative Disease,Neurology Process,Neuroscience,Proteolysis/Ubiquitin,Proteolytic Enzymes |
| Aditional Names: | Beta-secretase 1;3.4.23.46;Aspartyl protease 2;ASP2;Asp 2;Beta-site amyloid precursor protein cleaving enzyme 1;Beta-site APP cleaving enzyme 1;Memapsin-2;Membrane-associated aspartic protease 2;BACE1;BACE, KIAA1149; |
| Unit: | 30ul 100 ?l |
| Concentration: | Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
| Clonality: | Monoclonal |
| Price: | Consultar |
| Format: | Liquid |
| Immunogen: | A synthesized peptide derived from human BACE1 |
| Host: | Rabbit |
| Reactivity: | Human, Mouse, Rat |
| Application: | IP,WB |
| Description: | Boster Bio Anti-BACE1/Bace Rabbit Monoclonal Antibody catalog # M00322. Tested in IP, WB applications. This antibody reacts with Human, Mouse, Rat. |
| Function: | Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble AP |
| Cell localization: | Membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network. Endoplasmic reticulum. Endosome. Cell surface. Cytoplasmic vesicle membrane. Membrane raft. Predominantly localized to the later Golgi/trans-Golgi network (TGN) and mini |
| Clone: | Clone: ABFF-2 |
| Isotype: | Rabbit IgG |
| Purification: | Affinity-chromatography |
| Storage conditions: | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Assay inforation: | WB 1:500-1:2000 IP 1:40 |