Supplier: | Boster |
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Reference: | M01139 |
Name: | Anti-IKB alpha NFKBIA Rabbit Monoclonal Antibody |
Category: | Antibody |
Subcategory: | Primary Antibodies,Rabbit Monoclonal Antibodies |
Research Area: | Cancer,Epigenetics and Nuclear Signaling,Immunology,Innate Immunity,NFKB Pathway,Nuclear Signaling,Nuclear Signaling Pathways,Signal Transduction,Signaling Pathway,TLR Signaling |
Aditional Names: | NF-kappa-B inhibitor alpha;I-kappa-B-alpha;IkB-alpha;IkappaBalpha;Major histocompatibility complex enhancer-binding protein MAD3;NFKBIA;IKBA, MAD3, NFKBI; |
Unit: | 30ul 100 ?l |
Concentration: | Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
Clonality: | Monoclonal |
Price: | Consultar |
Format: | Liquid |
Immunogen: | A synthesized peptide derived from human IKB alpha |
Host: | Rabbit |
Reactivity: | Human, Mouse, Rat |
Application: | IP,IF,IHC,ICC,WB |
Description: | Boster Bio Anti-IKB alpha NFKBIA Rabbit Monoclonal Antibody catalog # M01139. Tested in IP, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. |
Function: | Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubi |
Cell localization: | Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm by a nuclear localization signal (NLS) and a CRM1-dependent nuclear export. |
Clone: | Clone: HO-14 |
Isotype: | Rabbit IgG |
Purification: | Affinity-chromatography |
Storage conditions: | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Assay inforation: | WB 1:500-1:2000 IHC 1:50-1:200 ICC/IF 1:50-1:200 IP 1:30 |