| Supplier: | Boster |
|---|---|
| Reference: | M00221-1 |
| Name: | Anti-LRRK2 Rabbit Monoclonal Antibody |
| Category: | Antibody |
| Subcategory: | Primary Antibodies,Rabbit Monoclonal Antibodies |
| Research Area: | Neurodegenerative Disease,Neurology Process,Neuroscience |
| Aditional Names: | Leucine-rich repeat serine/threonine-protein kinase 2;2.7.11.1;Dardarin;LRRK2;PARK8; |
| Unit: | 30ul 100 ?l |
| Concentration: | Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
| Clonality: | Monoclonal |
| Price: | Consultar |
| Format: | Liquid |
| Immunogen: | A synthesized peptide derived from human LRRK2 |
| Host: | Rabbit |
| Reactivity: | Human, Mouse |
| Application: | IF,IHC,ICC,WB |
| Description: | Boster Bio Anti-LRRK2 Rabbit Monoclonal Antibody catalog # M00221-1. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse. |
| Function: | Positively regulates autophagy through a calcium- dependent activation of the CaMKK/AMPK signaling pathway. The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH, and calcium release |
| Cell localization: | Membrane; Peripheral membrane protein. Cytoplasm. Perikaryon. Mitochondrion. Golgi apparatus. Cell projection, axon. Cell projection, dendrite. Endoplasmic reticulum. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane |
| Clone: | Clone: BBG-12 |
| Isotype: | Rabbit IgG |
| Purification: | Affinity-chromatography |
| Storage conditions: | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Assay inforation: | WB 1:500-1:2000 IHC 1:50-1:200 ICC/IF 1:50-1:200 |