Supplier: | Boster |
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Reference: | M03790 |
Name: | Anti-Smac/Diablo Rabbit Monoclonal Antibody |
Category: | Antibody |
Subcategory: | Primary Antibodies,Rabbit Monoclonal Antibodies |
Research Area: | Apoptosis,Cancer,Cell Biology,Cell Death,Invasion/Microenvironment,Metabolism,Metabolism Processes,Mitochondrial,Mitochondrial Markers,Mitochondrial Metabolism,Pathways and Processes,Receptors |
Aditional Names: | Diablo homolog, mitochondrial;Direct IAP-binding protein with low pI;Second mitochondria-derived activator of caspase;Smac;DIABLO;SMAC; |
Unit: | 30ul 100 ?l |
Concentration: | Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
Clonality: | Monoclonal |
Price: | Consultar |
Format: | Liquid |
Immunogen: | A synthesized peptide derived from human Smac/Diablo |
Host: | Rabbit |
Reactivity: | Human, Mouse, Rat |
Application: | Flow Cytometry,IP,IF,IHC,ICC,WB |
Description: | Boster Bio Anti-Smac/Diablo Rabbit Monoclonal Antibody catalog # M03790. Tested in Flow Cytometry, IP, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. |
Function: | Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP). Inhibits the activity of BIRC6/bruce by inhibiting its binding to caspases. Isoform |
Cell localization: | Mitochondrion. Released into the cytosol when cells undergo apoptosis. |
Clone: | Clone: FGG-4 |
Isotype: | Rabbit IgG |
Purification: | Affinity-chromatography |
Storage conditions: | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Assay inforation: | WB 1:1000-1:5000 IHC 1:50-1:200 ICC/IF 1:100-1:500 IP 1:50 Flow Cytometry 1:50 |