| Supplier: | Boster |
|---|---|
| Reference: | A12985 |
| Name: | Anti-ZC3H8/Fliz1 Antibody |
| Category: | Antibody |
| Subcategory: | Primary Antibodies |
| Research Area: | Chromatin Binding Proteins,DNA/RNA Binding,Domain Families,Epigenetics and Nuclear Signaling,Transcription,Transcription Factors,Zinc Finger |
| Aditional Names: | Zinc finger CCCH domain-containing protein 8;ZC3H8;ZC3HDC8; |
| Unit: | 100ul |
| Concentration: | 1 mg/ml |
| Clonality: | Polyclonal |
| Price: | Consultar |
| Format: | Liquid |
| Immunogen: | Synthesized peptide derived from internal of human Z |
| Host: | Rabbit |
| Reactivity: | Human |
| Application: | WB,IHC |
| Description: | Boster Bio Anti-ZC3H8/Fliz1 Antibody (Catalog # A12985). Tested in WB, IHC applications. This antibody reacts with Human. |
| Function: | Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Component |
| Cell localization: | Nucleus. Colocalizes with coilin in subnuclear cajal and histone locus bodies. Translocates in the LEC complex to cajal and histone locus bodies at snRNA genes in a ICE1-dependent manner. Associates to transcriptionally active chromatin at snRNA genes. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage conditions: | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Assay inforation: | Western blotting: 1:500~1:3000 Immunohistochemistry: 1:50~1:100 |