| Supplier: | Boster |
|---|---|
| Reference: | A05559 |
| Name: | Anti-SESN1/Pa26 Antibody |
| Category: | Antibody |
| Subcategory: | Primary Antibodies |
| Research Area: | Cell Biology,Metabolism,Obesity,Oxidative Stress,Pathways and Processes,Redox Metabolism |
| Aditional Names: | Sestrin-1;1.11.1.15;p53-regulated protein PA26;SESN1;PA26, SEST1; |
| Unit: | 100ul |
| Concentration: | 1 mg/ml |
| Clonality: | Polyclonal |
| Price: | Consultar |
| Format: | Liquid |
| Immunogen: | Synthesized peptide derived from internal of human S |
| Host: | Rabbit |
| Reactivity: | Human, Rat |
| Application: | WB,IHC |
| Description: | Boster Bio Anti-SESN1/Pa26 Antibody (Catalog # A05559). Tested in WB, IHC applications. This antibody reacts with Human, Rat. |
| Function: | Functions as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway through the GATOR complex. In absence of leucine, binds the GATOR subcomplex GATOR2 and prevents TORC1 signaling. Binding of leucine to SESN2 disrupts its |
| Cell localization: | Nucleus. Cytoplasm. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage conditions: | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Assay inforation: | Western blotting: 1:500~1:3000 Immunohistochemistry: 1:50~1:100 |