| Supplier: | Boster |
|---|---|
| Reference: | A03816 |
| Name: | Anti-Uba2/Sae2 Antibody |
| Category: | Antibody |
| Subcategory: | Primary Antibodies |
| Research Area: | Cell Biology,Proteasome / Ubiquitin,Proteolysis/Ubiquitin |
| Aditional Names: | SUMO-activating enzyme subunit 2;6.3.2.-;Anthracycline-associated resistance ARX;Ubiquitin-like 1-activating enzyme E1B;Ubiquitin-like modifier-activating enzyme 2;UBA2;SAE2, UBLE1B;HRIHFB2115; |
| Unit: | 100ul |
| Concentration: | 1 mg/ml |
| Clonality: | Polyclonal |
| Price: | Consultar |
| Format: | Liquid |
| Immunogen: | Synthesized peptide derived from C-terminal of human |
| Host: | Rabbit |
| Reactivity: | Human |
| Application: | WB,IHC |
| Description: | Boster Bio Anti-Uba2/Sae2 Antibody (Catalog # A03816). Tested in WB, IHC applications. This antibody reacts with Human. |
| Function: | The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/S |
| Cell localization: | Cytoplasm. Nucleus. Shuttles between the cytoplasm and the nucleus, sumoylation is required either for nuclear translocation or nuclear retention. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage conditions: | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Assay inforation: | Western blotting: 1:500~1:3000 Immunohistochemistry: 1:50~1:100 |