| Supplier: | Boster |
|---|---|
| Reference: | A02205 |
| Name: | Anti-DNA Polymerase thet POLQ Antibody |
| Category: | Antibody |
| Subcategory: | Primary Antibodies |
| Research Area: | DNA/RNA,DNA Synthesis,Epigenetics and Nuclear Signaling,RNA Polymerase,Transcription |
| Aditional Names: | POLQ;POLH;DNA polymerase theta;DNA polymerase eta |
| Unit: | 100ul |
| Concentration: | 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
| Clonality: | Polyclonal |
| Price: | Consultar |
| Format: | Liquid |
| Immunogen: | A peptide derived from human POLQ. Immunogen sequenc |
| Host: | Rabbit |
| Reactivity: | Human, Rat, Mouse |
| Application: | IHC-P,IF (paraffin),ELISA |
| Description: | Boster Bio Anti-DNA Polymerase thet POLQ Antibody (Catalog# A02205). Tested in IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Rat, Mouse. |
| Function: | DNA polymerase that promotes microhomology-mediated end- joining (MMEJ), an alternative non-homologous end-joining (NHEJ) machinery triggered in response to double-strand breaks in DNA (PubMed:25642963, PubMed:25643323). MMEJ is an error-prone repair pat |
| Cell localization: | Nucleus. Chromosome. Enriched in chromatin in response to ultaviolet (UV) light (PubMed:25642963). Binds to chromatin during early G1 (PubMed:24989122). |
| Isotype: | Rabbit IgG |
| Purification: | The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen. |
| Storage conditions: | Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Assay inforation: | Immunohistochemistry, 1:100 - 1:300 ELISA, 1:20000 Not yet tested in other applications. |