Supplier: | Boster |
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Reference: | A01484 |
Name: | Anti-Flap endonuclease 1 FEN1 Antibody |
Category: | Antibody |
Subcategory: | Primary Antibodies |
Research Area: | DNA/RNA,DNA Damage & Repair,Epigenetics and Nuclear Signaling |
Aditional Names: | Flap endonuclease 1;FEN-1;3.1.-.-;DNase IV;Flap structure-specific endonuclease 1;Maturation factor 1;MF1;hFEN-1;FEN1;RAD2; |
Unit: | 100ul |
Concentration: | 1 mg/ml |
Clonality: | Polyclonal |
Price: | Consultar |
Format: | Liquid |
Immunogen: | Synthesized peptide derived from internal of human F |
Host: | Rabbit |
Reactivity: | Human, Mouse, Rat |
Application: | WB,IHC,IF |
Description: | Boster Bio Anti-Flap endonuclease 1 FEN1 Antibody (Catalog # A01484). Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat. |
Function: | Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymera |
Cell localization: | Isoform 1: Nucleus, nucleolus. Nucleus, nucleoplasm. Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Storage conditions: | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Assay inforation: | Western blotting: 1:500~1:3000 Immunohistochemistry: 1:50~1:100 Immunofluorescence: 1:100~1:500 |