| Supplier: | Boster |
|---|---|
| Reference: | A00016-2 |
| Name: | Anti-p16 CDKN2A Monoclonal Antibody |
| Category: | Antibody |
| Subcategory: | Primary Antibodies,Monoclonal Antibodies |
| Aditional Names: | Tumor suppressor ARF;Alternative reading frame;ARF;Cyclin-dependent kinase inhibitor 2A;p14ARF;CDKN2A;CDKN2, MLM; |
| Unit: | 100ul |
| Clonality: | Monoclonal |
| Price: | Consultar |
| Format: | Liquid |
| Immunogen: | Purified recombinant fragment of p16 expressed in E. |
| Host: | Mouse |
| Reactivity: | Human, Rat |
| Application: | WB,IHC |
| Description: | Boster Bio Anti-p16 CDKN2A Monoclonal Antibody catalog # A00016-2. Tested in IHC, WB applications. This antibody reacts with Human, Rat. |
| Function: | Capable of inducing cell cycle arrest in G1 and G2 phases. Acts as a tumor suppressor. Binds to MDM2 and blocks its nucleocytoplasmic shuttling by sequestering it in the nucleolus. This inhibits the oncogenic action of MDM2 by blocking MDM2- induced degr |
| Cell localization: | Nucleus, nucleolus. Nucleus, nucleoplasm. |
| Clone: | Clone: 2D9A12 |
| Isotype: | IgG2b |
| Purification: | Affinity purification |
| Storage conditions: | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Assay inforation: | WB, 1:500-1:2000 IHC, 1:200-1:1000 |