Supplier: | Boster |
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Reference: | P03101 |
Name: | Anti-Phospho HIRA (Thr555) Antibody |
Category: | Antibody |
Subcategory: | Primary Antibodies |
Research Area: | Chromatin Remodeling,Developmental Biology,DNA/RNA,Epigenetics and Nuclear Signaling,Germ Cell Markers,Germline Stem Cells,Reproduction,RNA Processing,Stem Cells |
Aditional Names: | HIRA;DGCR1;HIR;TUPLE1;Protein HIRA;TUP1-like enhancer of split protein 1 |
Unit: | 100ul |
Concentration: | 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
Clonality: | Polyclonal |
Price: | Consultar |
Format: | Liquid |
Immunogen: | A peptide derived from human HIRA around the phospho |
Host: | Rabbit |
Reactivity: | Human, Mouse |
Application: | WB,IHC-P,IF,ICC,ELISA |
Description: | Boster Bio Anti-Phospho HIRA (Thr555) Antibody (Catalog# P03101). Tested in WB, IHC-P, IF, ICC, ELISA applications. This antibody reacts with Human, Mouse. |
Function: | Cooperates with ASF1A to promote replication-independent chromatin assembly. Required for the periodic repression of histone gene transcription during the cell cycle. Required for the formation of senescence-associated heterochromatin foci (SAHF) and eff |
Cell localization: | Nucleus. Nucleus, PML body. Primarily, though not exclusively, localized to the nucleus. Localizes to PML bodies immediately prior to onset of senescence. |
Isotype: | Rabbit IgG |
Purification: | The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide. |
Storage conditions: | Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Assay inforation: | Immunohistochemistry, 1:100 - 1:300 Immunofluorescence, 1:200 - 1:1000 ELISA, 1:10000 Not yet tested in other applications. |