| Supplier: | Boster |
|---|---|
| Reference: | A00558 |
| Name: | Anti-AIRE/Aire 1 Antibody |
| Category: | Antibody |
| Subcategory: | Primary Antibodies |
| Research Area: | Autoimmune,2339,Domain Families,Epigenetics and Nuclear Signaling,Immune System Diseases,Immunology,Transcription,Zinc Finger |
| Aditional Names: | Autoimmune regulator;Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein;APECED protein;AIRE;APECED; |
| Unit: | 100ul |
| Concentration: | 1 mg/ml |
| Clonality: | Polyclonal |
| Price: | Consultar |
| Format: | Liquid |
| Immunogen: | Synthesized peptide derived from internal of human A |
| Host: | Rabbit |
| Reactivity: | Human, Mouse |
| Application: | WB,IF |
| Description: | Boster Bio Anti-AIRE/Aire 1 Antibody (Catalog # A00558). Tested in WB, IF applications. This antibody reacts with Human, Mouse. |
| Function: | Transcriptional regulator that binds to DNA as a dimer or as a tetramer, but not as a monomer. Binds to G-doublets in an A/T-rich environment; the preferred motif is a tandem repeat of 5'-. ATTGGTTA-3' combined with a 5'-TTATTA-3' box. Binds to nucleosom |
| Cell localization: | Nucleus. Cytoplasm. Associated with tubular structures and in discrete nuclear dots resembling ND10 nuclear bodies. May shuttle between nucleus and cytoplasm. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage conditions: | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Assay inforation: | Western blotting: 1:500~1:3000 Immunofluorescence: 1:100~1:500 |