| Supplier: | Boster |
|---|---|
| Reference: | A06527 |
| Name: | Anti-RapGEF1/Grf2 Antibody |
| Category: | Antibody |
| Subcategory: | Primary Antibodies |
| Research Area: | G Protein Signaling,Ras Family,Regulators,Signal Transduction,Signaling Pathway,Small G Proteins |
| Aditional Names: | RAPGEF1;GRF2;Rap guanine nucleotide exchange factor 1;CRK SH3-binding GNRP;Guanine nucleotide-releasing factor 2;Protein C3G |
| Unit: | 100ul |
| Concentration: | 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
| Clonality: | Polyclonal |
| Price: | Consultar |
| Format: | Liquid |
| Immunogen: | A peptide derived from human RAPGEF1. Immunogen sequ |
| Host: | Rabbit |
| Reactivity: | Human, Rat, Mouse |
| Application: | IHC-P,IF (paraffin),ELISA |
| Description: | Boster Bio Anti-RapGEF1/Grf2 Antibody (Catalog# A06527). Tested in IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Rat, Mouse. |
| Function: | Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sus |
| Cell localization: | Early endosome. |
| Isotype: | Rabbit IgG |
| Purification: | The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen. |
| Storage conditions: | Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Assay inforation: | Immunohistochemistry, 1:100 - 1:300 ELISA, 1:5000 Not yet tested in other applications. |