| Supplier: | Boster |
|---|---|
| Reference: | A06496-1 |
| Name: | Anti-HAND1 Antibody |
| Category: | Antibody |
| Subcategory: | Primary Antibodies |
| Research Area: | Cardiogenesis,Cardiovascular,Developmental Biology,Epigenetics and Nuclear Signaling,Lineage Markers,Lineage Specification,Stem Cells,Transcription,Transcription Factors/Regulators |
| Aditional Names: | HAND1;BHLHA27;EHAND;Heart- and neural crest derivatives-expressed protein 1;Class A basic helix-loop-helix protein 27;bHLHa27;Extraembryonic tissues; heart, autonomic nervous system and neural crest derivatives-expressed protein 1;eH |
| Unit: | 100ul |
| Concentration: | 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
| Clonality: | Polyclonal |
| Price: | Consultar |
| Format: | Liquid |
| Immunogen: | A peptide derived from human HAND1. Immunogen sequen |
| Host: | Rabbit |
| Reactivity: | Human, Mouse, Rat |
| Application: | IHC-P,IF (paraffin),ELISA |
| Description: | Boster Bio Anti-HAND1 Antibody (Catalog# A06496-1). Tested in IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat. |
| Function: | Transcription factor that plays an essential role in both trophoblast-giant cells differentiation and in cardiac morphogenesis. In the adult, could be required for ongoing expression of cardiac-specific genes. Binds the DNA sequence 5'- NRTCTG-3' (non-ca |
| Cell localization: | Nucleus, nucleoplasm. Nucleus, nucleolus. Interaction with MDFIC sequesters it into the nucleolus, preventing the transcription factor activity. Phosphorylation by PLK4 disrupts the interaction with MDFIC and releases it from the nucleolus, leading to tra |
| Isotype: | Rabbit IgG |
| Purification: | The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen. |
| Storage conditions: | Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Assay inforation: | Immunohistochemistry, 1:100 - 1:300 ELISA, 1:20000 Not yet tested in other applications. |