| Supplier: | Boster |
|---|---|
| Reference: | A30434 |
| Name: | Anti-Parkin PARK2 Antibody |
| Category: | Antibody |
| Subcategory: | Primary Antibodies |
| Research Area: | Cell Biology,Metabolism,Mitochondrial Metabolism,Neurodegenerative Disease,Neurology Process,Neuroscience,Pathways and Processes,Proteasome / Ubiquitin,Proteolysis/Ubiquitin,Ring Finger E3 Ligase,Ubiquitin E3 Enzymes |
| Aditional Names: | PARK2;PRKN;E3 ubiquitin-protein ligase parkin;Parkinson juvenile disease protein 2;Parkinson disease protein 2 |
| Unit: | 100ul |
| Concentration: | 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
| Clonality: | Polyclonal |
| Price: | Consultar |
| Format: | Liquid |
| Immunogen: | A peptide derived from human Parkin. Immunogen seque |
| Host: | Rabbit |
| Reactivity: | Human, Mouse, Rat |
| Application: | WB,IHC-P,IF (paraffin),ELISA |
| Description: | Boster Bio Anti-Parkin PARK2 Antibody (Catalog# A30434). Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat. |
| Function: | Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins, such as BCL2, SYT11, CCNE1, GPR37, RHOT1/MIRO1, MFN1, MFN2, STUB1, SNCAIP, SEPT5, TOMM20, USP30, ZNF746 and AIM |
| Cell localization: | Cytoplasm, cytosol. Nucleus. Endoplasmic reticulum. Mitochondrion. Mainly localizes in the cytosol. Co-localizes with SYT11 in neutrites. Co-localizes with SNCAIP in brainstem Lewy bodies. Mitochondrial localization gradually increases with cellular growt |
| Isotype: | Rabbit IgG |
| Purification: | The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen. |
| Storage conditions: | Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Assay inforation: | Western Blot, 1:500 - 1:2000 Immunohistochemistry, 1:100 - 1:300 ELISA, 1:10000 Not yet tested in other applications. |