Supplier: | Boster |
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Reference: | A00016-3 |
Name: | Anti-p16 CDKN2A Monoclonal Antibody |
Category: | Antibody |
Subcategory: | Primary Antibodies,Monoclonal Antibodies |
Aditional Names: | Tumor suppressor ARF;Alternative reading frame;ARF;Cyclin-dependent kinase inhibitor 2A;p14ARF;CDKN2A;CDKN2, MLM; |
Unit: | 100ul |
Clonality: | Monoclonal |
Price: | Consultar |
Format: | Liquid |
Immunogen: | Purified recombinant fragment of p16 expressed in E. |
Host: | Mouse |
Reactivity: | Human, Mouse, Rat |
Application: | ELISA,IHC-P,WB |
Description: | Boster Bio Anti-p16 CDKN2A Monoclonal Antibody catalog # A00016-3. Tested in ELISA, IHC-P, WB applications. This antibody reacts with Human, Mouse, Rat. |
Function: | Capable of inducing cell cycle arrest in G1 and G2 phases. Acts as a tumor suppressor. Binds to MDM2 and blocks its nucleocytoplasmic shuttling by sequestering it in the nucleolus. This inhibits the oncogenic action of MDM2 by blocking MDM2- induced degr |
Cell localization: | Nucleus, nucleolus. Nucleus, nucleoplasm. |
Clone: | Clone: 1E12E1 |
Isotype: | IgG1 |
Purification: | Affinity purification |
Storage conditions: | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Assay inforation: | ELISA 1:10000 IHC 1:200-1:1000 WB 1:500-1:2000 |