| Supplier: | Boster |
|---|---|
| Reference: | A07077-1 |
| Name: | Anti-Diacylglycerol kinase eta DGKH Antibody |
| Category: | Antibody |
| Subcategory: | Primary Antibodies |
| Research Area: | Protein Phosphorylation,Ser/Thr Kinases,Signal Transduction |
| Aditional Names: | DGKH;Diacylglycerol kinase eta;DAG kinase eta;Diglyceride kinase eta;DGK-eta |
| Unit: | 100ul |
| Concentration: | 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
| Clonality: | Polyclonal |
| Price: | Consultar |
| Format: | Liquid |
| Immunogen: | A peptide derived from human DGKH. Immunogen sequenc |
| Host: | Rabbit |
| Reactivity: | Human, Mouse |
| Application: | IHC-P,IF,ICC,ELISA |
| Description: | Boster Bio Anti-Diacylglycerol kinase eta DGKH Antibody (Catalog# A07077-1). Tested in IHC-P, IF, ICC, ELISA applications. This antibody reacts with Human, Mouse. |
| Function: | Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). Plays a key role in promoting cell growth. Activates the Ras/B-Raf/C-Raf/MEK/ERK signaling pathway induced by EGF. Regulates the recruitment of RAF1 and BRAF from cytoplasm to membra |
| Cell localization: | Cytoplasm. Cell membrane. Translocated from the cytoplasm to endosomes in response to stress stimuli (PubMed:12810723). Isoform 2 is rapidly relocated back to the cytoplasm upon removal of stress stimuli, whereas isoform 1 exhibits sustained endosomal ass |
| Isotype: | Rabbit IgG |
| Purification: | The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen. |
| Storage conditions: | Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Assay inforation: | Immunohistochemistry, 1:100 - 1:300 Immunofluorescence, 1:200 - 1:1000 ELISA, 1:20000 Not yet tested in other applications. |