| Supplier: | Boster |
|---|---|
| Reference: | A05559-1 |
| Name: | Anti-SESN1/Pa26 Antibody |
| Category: | Antibody |
| Subcategory: | Primary Antibodies |
| Research Area: | Cell Biology,Metabolism,Obesity,Oxidative Stress,Pathways and Processes,Redox Metabolism |
| Aditional Names: | SESN1;PA26;SEST1;Sestrin-1;p53-regulated protein PA26 |
| Unit: | 100ul |
| Concentration: | 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
| Clonality: | Polyclonal |
| Price: | Consultar |
| Format: | Liquid |
| Immunogen: | A peptide derived from human SESN1. Immunogen sequen |
| Host: | Rabbit |
| Reactivity: | Human, Mouse, Rat |
| Application: | WB,IHC-P,IF (paraffin),ELISA |
| Description: | Boster Bio Anti-SESN1/Pa26 Antibody (Catalog# A05559-1). Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat. |
| Function: | Functions as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway through the GATOR complex. In absence of leucine, binds the GATOR subcomplex GATOR2 and prevents TORC1 signaling. Binding of leucine to SESN2 disrupts its |
| Cell localization: | Nucleus. Cytoplasm. |
| Isotype: | Rabbit IgG |
| Purification: | The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen. |
| Storage conditions: | Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Assay inforation: | Western Blot, 1:500 - 1:2000 Immunohistochemistry, 1:100 - 1:300 ELISA, 1:20000 Not yet tested in other applications. |