Supplier: | Boster |
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Reference: | M00382 |
Name: | Anti-Cdc20 (Cell Division Cycle Protein 20) Monoclonal Antibody |
Category: | Antibody |
Subcategory: | Primary Antibodies,Monoclonal Antibodies |
Research Area: | Cell Biology,Proteasome / Ubiquitin,Proteolysis/Ubiquitin |
Aditional Names: | Cell division cycle protein 20 homolog;p55CDC;CDC20; |
Unit: | 100ug |
Concentration: | Purified antibody with BSA and azide at 200ug/ml |
Clonality: | Monoclonal |
Price: | Consultar |
Format: | Liquid |
Immunogen: | Recombinant human Cdc20 protein |
Host: | Mouse |
Reactivity: | Human |
Application: | IHC |
Description: | Boster Bio Anti-Cdc20 (Cell Division Cycle Protein 20) Monoclonal Antibody (Catalog # M00382). Tested in IHC applications. This antibody reacts with Human. |
Function: | Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase |
Cell localization: | Cytoplasmic |
Clone: | Clone: CDC20/1102 |
Isotype: | IgG1, kappa |
Purification: | 200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G. |
Storage conditions: | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
Assay inforation: | Immunohistochemistry (Formalin-fixed) (2-4ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes) Optimal diluti |