| Supplier: | Boster |
|---|---|
| Reference: | A30763 |
| Name: | Anti-SGOL2 SGO2 Antibody |
| Category: | Antibody |
| Subcategory: | Primary Antibodies |
| Aditional Names: | SGOL2;Shugoshin-like 2;Shugoshin-2;Sgo2;Tripin |
| Unit: | 100ul |
| Concentration: | 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
| Clonality: | Polyclonal |
| Price: | Consultar |
| Format: | Liquid |
| Immunogen: | A peptide derived from human SGOL2. Immunogen sequen |
| Host: | Rabbit |
| Reactivity: | Human, Rat, Mouse |
| Application: | IHC-P,IF (paraffin),ELISA |
| Description: | Boster Bio Anti-SGOL2 SGO2 Antibody (Catalog# A30763). Tested in IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Rat, Mouse. |
| Function: | Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres from cleavage by separase. During meiosis, protects centromeric cohesion |
| Cell localization: | Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. During meiosis I, accumulates at centromeres during diplotene, and colocalizes differentially with the cohesin subunits RAD21 and REC8 at metaphase I centromeres (By similarity). SGO2 a |
| Isotype: | Rabbit IgG |
| Purification: | The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen. |
| Storage conditions: | Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Assay inforation: | Immunohistochemistry, 1:100 - 1:300 ELISA, 1:10000 Not yet tested in other applications. |