| Supplier: | Boster |
|---|---|
| Reference: | P30915 |
| Name: | Anti-Phospho Erbin (Tyr1104) Antibody |
| Category: | Antibody |
| Subcategory: | Primary Antibodies |
| Research Area: | G Protein Signaling,Ras Family,Signal Transduction,Signaling Pathway,Small G Proteins |
| Aditional Names: | ERBB2IP;ERBIN;KIAA1225;LAP2;Protein LAP2;Densin-180-like protein;Erbb2-interacting protein;Erbin |
| Unit: | 100ul |
| Concentration: | 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
| Clonality: | Polyclonal |
| Price: | Consultar |
| Format: | Liquid |
| Immunogen: | A phospho-peptide derived from human Erbin around th |
| Host: | Rabbit |
| Reactivity: | Human, Rat, Mouse |
| Application: | WB,ELISA |
| Description: | Boster Bio Anti-Phospho Erbin (Tyr1104) Antibody (Catalog# P30915). Tested in WB, ELISA applications. This antibody reacts with Human, Rat, Mouse. |
| Function: | Acts as an adapter for the receptor ERBB2, in epithelia. By binding the unphosphorylated 'Tyr-1248' of receptor ERBB2, it may contribute to stabilize this unphosphorylated state (PubMed:16203728). Inhibits NOD2-dependent NF-kappa-B signaling and proinfla |
| Cell localization: | Cell junction, hemidesmosome. Nucleus membrane. Basolateral cell membrane. Found in hemidesmosomes, which are cell-substrate adhesion complexes in stratified epithelia. In transfected cells, either diffusely distributed over the cytoplasm or concentrated |
| Isotype: | Rabbit IgG |
| Purification: | The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide. |
| Storage conditions: | Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Assay inforation: | Western Blot, 1:500 - 1:2000 ELISA, 1:10000 Not yet tested in other applications. |