Supplier: | Boster |
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Reference: | M00173 |
Name: | Anti-p27Kip1 (Mitotic Inhibitor/Suppressor Protein) CDKN1B Monoclonal Antibody |
Category: | Antibody |
Subcategory: | Primary Antibodies,Monoclonal Antibodies |
Research Area: | Cancer,Cell Biology,Cell Cycle,Cell Cycle Inhibitors,Epigenetics and Nuclear Signaling |
Aditional Names: | Cyclin-dependent kinase inhibitor 1B;Cyclin-dependent kinase inhibitor p27;p27Kip1;CDKN1B;KIP1; |
Unit: | 100ug |
Concentration: | Purified antibody with BSA and azide at 200ug/ml |
Clonality: | Monoclonal |
Price: | Consultar |
Format: | Liquid |
Immunogen: | Mouse recombinant p27 protein (DCS-72.F6); Recombina |
Host: | Mouse |
Reactivity: | Human, Monkey, Mouse, Rat |
Application: | Flow Cytometry,IF,WB,IHC |
Description: | Boster Bio Anti-p27Kip1 (Mitotic Inhibitor/Suppressor Protein) CDKN1B Monoclonal Antibody (Catalog # M00173). Tested in Flow Cytometry, IF, WB, IHC applications. This antibody reacts with Human, Monkey, Mouse, Rat. |
Function: | Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1- CDK4 c |
Cell localization: | Nuclear |
Clone: | Clone: DCS-72.F6 + KIP1/769 |
Isotype: | IgG1, kappa |
Purification: | 200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G. |
Storage conditions: | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
Assay inforation: | Flow Cytometry (1-2ug/million cells) Immunofluorescence (1-2ug/ml) Western Blot (1-2ug/ml) Immunohistochemistry (Formalin-fixed) (0.25-0.5ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris |