CDNF Cerebral Dopamine Neurotrophic Factor Rat Recombinant Protein

Supplier: Boster
Reference: PROTP0C5I0
Name: CDNF Cerebral Dopamine Neurotrophic Factor Rat Recombinant Protein
Category: Protein
Subcategory: Recombinant Proteins
Aditional Names: Cerebral neurotrophic factor; ARMET-like protein 1; Arginine-rich protein mutated in early stage tumors-like 1; Conserved neurotrophic factor; Cdnf; Armetl1
Unit: 5ug 20ug 1mg
Price: Consultar
Format: Sterile Filtered White lyophilized (freeze-dried) powder.
Reactivity: Rat
Description: CDNF Rat Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 163 amino acids and having a molecular mass of 18.8kDa. The CDNF is purified by proprietary chromatographic techniques.
Function: Trophic factor for dopamine neurons. Prevents the 6- hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons
Cell localization: Secreted
Purification: Greater than 97.0% as determined by (a) Analysis by RP-HPLC and (b) Analysis by SDS-PAGE.
Storage conditions: Lyophilized CDNF although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CDNF should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a c
Aa sequence: QGLEAGVRSR ADCEVCKEFL NRFYNSLLTR GIDFSVDTIE EELISFCADT KGKENRLCYY LGATKDSATK ILGEVTRPMS VHMPTVKICE KLKKMDSQIC ELKYEKKLDL ESVDLWKMRV AELKQILHSW GEECRACAEK HDYVNLIKEL APKYVETRPQ TEL