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Streptolysin-O Streptococcus Pyogenes Recombinant Protein

Supplier: Boster
Reference: PROTP0DF96
Name: Streptolysin-O Streptococcus Pyogenes Recombinant Protein
Category: Protein
Subcategory: Recombinant Proteins
Aditional Names: Streptolysin O; Thiol-activated cytolysin; slo
Unit: 20ug 100ug 1mg
Price: Consultar
Format: Sterile Filtered white lyophilized powder.
Reactivity: Streptococcus pyogenes
Description: Recombinant Streptococcus Pyogenes Streptolysin-O produced in E.coli is a single, non-glycosylated, polypeptide chain containing 538 amino acids and having a molecular mass of 60.1kDa. The Streptolysin-O is purified by proprietary chromatographic techniqu
Function: Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation
Cell localization: Secreted. Host cell membrane
Purification: Greater than 97.0% as determined by (a) Analysis by RP-HPLC and (b) Analysis by SDS-PAGE.
Storage conditions: Lyophilized Streptolysin-O although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Streptolysin-O should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is re
Aa sequence: NKQNTASTET TTTNEQPKPE SSELTTEKAG QKTDDMLNSN DMIKLAPKEM PLESAEKEEK KSEDKKKSEE DHTEEINDKI YSLNYNELEV LAKNGETIEN FVPKEGVKKA DKFIVIERKK KNINTTPVDI SIIDSVTDRT YPAALQLANK GFTENKPDAV VTKRNPQKIH IDLPGMGDKA TVEVNDPTYA NVSTAIDNLV NQWHDNYSGG NTLPARTQYT ESMVYSKSQI EA
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