HB-EGF Proheparin-Binding EGF-like Growth Factor Human Recombinant Protein

Supplier: Boster
Reference: PROTQ99075
Name: HB-EGF Proheparin-Binding EGF-like Growth Factor Human Recombinant Protein
Category: Protein
Subcategory: Recombinant Proteins
Aditional Names: HBEGF; DTR; DTS; HEGFL; HB-EGF; Diphtheria toxin receptor; DT-R; DTSF
Unit: 10ug 50ug 1mg
Price: Consultar
Format: Sterile Filtered White lyophilized (freeze-dried) powder.
Reactivity: Human
Description: HB-EGF Human Recombinant produced in E. coli is a single, non-glycosylated, polypeptide chain containing 87 amino acids and having a molecular mass of 9.9kDa. The HB-EGF is purified by proprietary chromatographic techniques.
Function: Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mito
Cell localization: Heparin-binding EGF-like growth factor: Secreted, extracellular space. Mature HB-EGF is released into the extracellular space and probably binds to a receptor.
Purification: Greater than 95.0% as determined by SDS-PAGE.
Storage conditions: Lyophilized Human HB-EGF Recombinant although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution HB-EGF should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is
Aa sequence: MDLQEADLDL LRVTLSSKPQ ALATPNKEEH GKRKKKGKGL GKKRDPCLRK YKDFCIHGEC KYVKELRAPS CICHPGYHGE RCHGLSL